DAZ1 Peptide - N-terminal region (AAP58711)

Data Sheet
Sku AAP58711
Old sku AAPP35911
Price $99.00
Name DAZ1 Peptide - N-terminal region (AAP58711)
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Size 100 ug
Gene DAZ1
Alias symbols DAZ, SPGY
Gene id 1617
Description of target DAZ1 is a RNA-binding protein that plays an essential role in spermatogenesis. DAZ1 may act by binding to the 3'-UTR of mRNAs and regulating their translation.This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains three copies of the 10.8 kb repeat. However, no transcripts containing three copies of the RRM domain have been described; thus the RefSeq for this gene contains only two RRM domains. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Swissprot id Q9NQZ3
Protein accession num NP_004072
Nucleotide accession num NM_004081
Protein size 579 amino acids
Molecular weight 64kDa
Application WB
Quality control The peptide is characterized by mass spectroscopy
Key reference Stouffs,K., (2008) Hum. Reprod. 23 (5), 1193-1199
Description This is a synthetic peptide designed for use in combination with anti-DAZ1 antibody (Catalog #: ARP58711_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days

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