Sku |
AAP58687 |
Old sku |
AAPP35934 |
Price |
$99.00 |
Name |
UBA1 Peptide - N-terminal region (AAP58687) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
UBA1 |
Alias symbols |
A1S9, A1S9T, A1ST, GXP1, MGC4781, UBA1A, UBE1, UBE1X, AMCX1, POC20, SMAX2 |
Gene id |
7317 |
Description of target |
UBA1 activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin-E1 thioester and free AMP.The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described. |
Swissprot id |
P22314 |
Protein accession num |
NP_003325 |
Nucleotide accession num |
NM_003334 |
Protein size |
1058 amino acids |
Molecular weight |
116kDa |
Application |
WB |
Partner proteins |
CDK1,GAN,HSPH1,MGMT,SEMA3F,TAF9,TMCC2,TSSC4,BARD1,BRCA1,BTRC,CBL,DZIP3,FANCD2,HGS,HSPH1,NEDD4,NEDD4L,POLR2A,RBCK1,STUB1,UBC |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Ramser,J., (2008) Am. J. Hum. Genet. 82 (1), 188-193 |
Description |
This is a synthetic peptide designed for use in combination with anti-UBA1 antibody (Catalog #: ARP58687_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |