UBA1 Peptide - N-terminal region (AAP58687)

Data Sheet
 
Sku AAP58687
Old sku AAPP35934
Price $99.00
Name UBA1 Peptide - N-terminal region (AAP58687)
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Size 100 ug
Gene UBA1
Alias symbols A1S9, A1S9T, A1ST, GXP1, MGC4781, UBA1A, UBE1, UBE1X, AMCX1, POC20, SMAX2
Gene id 7317
Description of target UBA1 activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin-E1 thioester and free AMP.The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described.
Swissprot id P22314
Protein accession num NP_003325
Nucleotide accession num NM_003334
Protein size 1058 amino acids
Molecular weight 116kDa
Application WB
Partner proteins CDK1,GAN,HSPH1,MGMT,SEMA3F,TAF9,TMCC2,TSSC4,BARD1,BRCA1,BTRC,CBL,DZIP3,FANCD2,HGS,HSPH1,NEDD4,NEDD4L,POLR2A,RBCK1,STUB1,UBC
Quality control The peptide is characterized by mass spectroscopy
Key reference Ramser,J., (2008) Am. J. Hum. Genet. 82 (1), 188-193
Description This is a synthetic peptide designed for use in combination with anti-UBA1 antibody (Catalog #: ARP58687_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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