PPP1CA Peptide - N-terminal region (AAP58652)

Data Sheet
 
Sku AAP58652
Old sku AAPP35789
Price $99.00
Name PPP1CA Peptide - N-terminal region (AAP58652)
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Size 100 ug
Gene PPP1CA
Alias symbols MGC15877, MGC1674, PP-1A, PPP1A, PP1alpha
Gene id 5499
Description of target PPP1CA is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory.The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Swissprot id Q07161
Protein accession num NP_001008709
Nucleotide accession num NM_001008709
Protein size 341 amino acids
Molecular weight 38kDa
Application WB
Partner proteins CAV1,AKAP1,AKAP11,AKAP9,APAF1,AURKA,BAD,BAX,BCL2,BCL2L1,BCL2L2,BRCA1,C1orf114,CAD,CASC5,CDC5L,CDH1,CSRNP2,CUL1,DCX,EIF2AK2,FXYD1,H2AFX,HEYL,HSPA4,ID2,KANK1,KIAA1949,KIF13A,KIF18A,MAPK1,MAPK3,MYO16,NEK2,NOM1,PCDH7,PCNA,PHACTR1,PHACTR3,PHACTR4,PLCL2,PPP1CA,PPP1R10,PPP1R11,PPP1R13B,PPP1R13L,PPP1R15A,PPP1R15B,PPP1R1B,PPP1R2,PPP1R3B,PPP1R8,PPP1R9A,PPP1R9B,PPP2CA,PRKCD,PTEN,RB1,SKP1,SPRED1,STAM,STAU1,SYTL2,TP53,TP53BP2,TPRN,TUSC3,VDR,YLPM1,ZFYVE16,ZFYVE9,ACTA1,AKAP11,BCL2L1,BCL2L2,BRCA1,CDC5L,EED,EIF2AK2,GSK3B,HCFC1,HSPA8,KCNQ1,LMTK2,NOC2L,PHACTR1,PHACTR3,PPP1R10,PPP1R15A,PPP1R8,PPP1R9B,RPAP2,RPAP3,RRP1B,RUVBL2,RYR2,Rrp1b,SMARCB1,TGFBR1,TGFBR2
Quality control The peptide is characterized by mass spectroscopy
Key reference Lesage,B., (2007) Biochemistry 46 (31), 8909-8919
Description This is a synthetic peptide designed for use in combination with anti-PPP1CA antibody (Catalog #: ARP58652_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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