Sku |
AAP58652 |
Old sku |
AAPP35789 |
Price |
$99.00 |
Name |
PPP1CA Peptide - N-terminal region (AAP58652) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
PPP1CA |
Alias symbols |
MGC15877, MGC1674, PP-1A, PPP1A, PP1alpha |
Gene id |
5499 |
Description of target |
PPP1CA is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory.The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Swissprot id |
Q07161 |
Protein accession num |
NP_001008709 |
Nucleotide accession num |
NM_001008709 |
Protein size |
341 amino acids |
Molecular weight |
38kDa |
Application |
WB |
Partner proteins |
CAV1,AKAP1,AKAP11,AKAP9,APAF1,AURKA,BAD,BAX,BCL2,BCL2L1,BCL2L2,BRCA1,C1orf114,CAD,CASC5,CDC5L,CDH1,CSRNP2,CUL1,DCX,EIF2AK2,FXYD1,H2AFX,HEYL,HSPA4,ID2,KANK1,KIAA1949,KIF13A,KIF18A,MAPK1,MAPK3,MYO16,NEK2,NOM1,PCDH7,PCNA,PHACTR1,PHACTR3,PHACTR4,PLCL2,PPP1CA,PPP1R10,PPP1R11,PPP1R13B,PPP1R13L,PPP1R15A,PPP1R15B,PPP1R1B,PPP1R2,PPP1R3B,PPP1R8,PPP1R9A,PPP1R9B,PPP2CA,PRKCD,PTEN,RB1,SKP1,SPRED1,STAM,STAU1,SYTL2,TP53,TP53BP2,TPRN,TUSC3,VDR,YLPM1,ZFYVE16,ZFYVE9,ACTA1,AKAP11,BCL2L1,BCL2L2,BRCA1,CDC5L,EED,EIF2AK2,GSK3B,HCFC1,HSPA8,KCNQ1,LMTK2,NOC2L,PHACTR1,PHACTR3,PPP1R10,PPP1R15A,PPP1R8,PPP1R9B,RPAP2,RPAP3,RRP1B,RUVBL2,RYR2,Rrp1b,SMARCB1,TGFBR1,TGFBR2 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Lesage,B., (2007) Biochemistry 46 (31), 8909-8919 |
Description |
This is a synthetic peptide designed for use in combination with anti-PPP1CA antibody (Catalog #: ARP58652_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
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Tips |
See our General FAQ page. |
Availability |
In Stock |
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