| Sku |
AAP58648 |
| Old sku |
AAPP35785 |
| Price |
$99.00 |
| Name |
OGDH Peptide - N-terminal region (AAP58648) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
OGDH |
| Alias symbols |
AKGDH, E1k, OGDC |
| Gene id |
4967 |
| Description of target |
The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO2. It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitocondrial matrix and uses thiamine pyrophosphate as a cofactor. A congential deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. |
| Swissprot id |
Q96DD3 |
| Protein accession num |
NP_001003941 |
| Nucleotide accession num |
NM_001003941 |
| Protein size |
427 amino acids |
| Molecular weight |
47kDa |
| Application |
WB |
| Partner proteins |
DLD,DLST,PLSCR1,DLD,DLST,PLSCR1,USP13 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
van (2007) Am. J. Med. Genet. A 143 (7), 763-767 |
| Description |
This is a synthetic peptide designed for use in combination with anti-OGDH antibody (Catalog #: ARP58648_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
