Sku |
AAP58624 |
Old sku |
AAPP35761 |
Price |
$99.00 |
Name |
FN3KRP Peptide - N-terminal region (AAP58624) |
Purchase info |
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|
Size |
100 ug |
Gene |
FN3KRP |
Alias symbols |
FLJ12171, FN3KL |
Gene id |
79672 |
Description of target |
FN3KRP phosphorylates psicosamines and ribulosamines, but not fructosamines, on the third carbon of the sugar moiety. Protein-bound psicosamine 3-phosphates and ribulosamine 3-phosphates are unstable and decompose under physiological conditions. Thus phosphorylation leads to deglycation.FN3KRP and FN3K (MIM 608425) protect proteins from nonenzymatic glycation by phosphorylating the modified amino acid. This phosphorylation destabilizes the sugar-amine linkage and leads to spontaneous decomposition (Conner et al., 2004 [PubMed 15381090]).[supplied by OMIM]. |
Swissprot id |
Q9HA64 |
Protein accession num |
NP_078895 |
Nucleotide accession num |
NM_024619 |
Protein size |
309 amino acids |
Molecular weight |
34kDa |
Application |
WB |
Partner proteins |
USP43 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Szwergold,B., (2007) Biochem. Biophys. Res. Commun. 361 (4), 870-875 |
Description |
This is a synthetic peptide designed for use in combination with anti-FN3KRP antibody (Catalog #: ARP58624_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |