FN3KRP Peptide - N-terminal region (AAP58624)

Data Sheet
 
Sku AAP58624
Old sku AAPP35761
Price $99.00
Name FN3KRP Peptide - N-terminal region (AAP58624)
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Size 100 ug
Gene FN3KRP
Alias symbols FLJ12171, FN3KL
Gene id 79672
Description of target FN3KRP phosphorylates psicosamines and ribulosamines, but not fructosamines, on the third carbon of the sugar moiety. Protein-bound psicosamine 3-phosphates and ribulosamine 3-phosphates are unstable and decompose under physiological conditions. Thus phosphorylation leads to deglycation.FN3KRP and FN3K (MIM 608425) protect proteins from nonenzymatic glycation by phosphorylating the modified amino acid. This phosphorylation destabilizes the sugar-amine linkage and leads to spontaneous decomposition (Conner et al., 2004 [PubMed 15381090]).[supplied by OMIM].
Swissprot id Q9HA64
Protein accession num NP_078895
Nucleotide accession num NM_024619
Protein size 309 amino acids
Molecular weight 34kDa
Application WB
Partner proteins USP43
Quality control The peptide is characterized by mass spectroscopy
Key reference Szwergold,B., (2007) Biochem. Biophys. Res. Commun. 361 (4), 870-875
Description This is a synthetic peptide designed for use in combination with anti-FN3KRP antibody (Catalog #: ARP58624_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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