SOD2 Peptide - N-terminal region (AAP58529)

Data Sheet
 
Sku AAP58529
Old sku AAPP34826
Price $99.00
Name SOD2 Peptide - N-terminal region (AAP58529)
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Size 100 ug
Gene SOD2
Alias symbols IPO-B, MNSOD, Mn-SOD, IPOB, MVCD6
Gene id 6648
Description of target SOD2 is a member of the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene encoding SOD2 have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer.This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Swissprot id P04179
Protein accession num NP_000627
Nucleotide accession num NM_000636
Protein size 222 amino acids
Molecular weight 24kDa
Application WB
Partner proteins GET4,HDHD2,NOL12,RAB4A,RPS3A,SOD2,AURKA,NOL12,RPS3A
Quality control The peptide is characterized by mass spectroscopy
Key reference Martin,R.C., (2008) DNA Cell Biol. 27 (6), 321-323
Description This is a synthetic peptide designed for use in combination with anti-SOD2 antibody (Catalog #: ARP58529_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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