PNPO Peptide - N-terminal region (AAP58515)

Data Sheet
Sku AAP58515
Old sku AAPP34535
Price $99.00
Name PNPO Peptide - N-terminal region (AAP58515)
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Size 100 ug
Alias symbols FLJ10535, PDXPO
Gene id 55163
Description of target PNPO catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine.Vitamin B6, or pyridoxal 5-prime-phosphate (PLP), is critical for normal cellular function, and some cancer cells have notable differences in vitamin B6 metabolism compared to their normal counterparts. The rate-limiting enzyme in vitamin B6 synthesis is pyridoxine-5-prime-phosphate (PNP) oxidase (PNPO; EC[supplied by OMIM].
Swissprot id Q9NVS9
Protein accession num NP_060599
Nucleotide accession num NM_018129
Protein size 261 amino acids
Molecular weight 29kDa
Application WB
Quality control The peptide is characterized by mass spectroscopy
Key reference Song,H., Schizophr. Res. 97 (1-3), 264-270 (2007)
Description This is a synthetic peptide designed for use in combination with anti-PNPO antibody (Catalog #: ARP58515_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days

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