| Sku |
AAP58515 |
| Old sku |
AAPP34535 |
| Price |
$99.00 |
| Name |
PNPO Peptide - N-terminal region (AAP58515) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
PNPO |
| Alias symbols |
FLJ10535, PDXPO |
| Gene id |
55163 |
| Description of target |
PNPO catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine.Vitamin B6, or pyridoxal 5-prime-phosphate (PLP), is critical for normal cellular function, and some cancer cells have notable differences in vitamin B6 metabolism compared to their normal counterparts. The rate-limiting enzyme in vitamin B6 synthesis is pyridoxine-5-prime-phosphate (PNP) oxidase (PNPO; EC 1.4.3.5).[supplied by OMIM]. |
| Swissprot id |
Q9NVS9 |
| Protein accession num |
NP_060599 |
| Nucleotide accession num |
NM_018129 |
| Protein size |
261 amino acids |
| Molecular weight |
29kDa |
| Application |
WB |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Song,H., Schizophr. Res. 97 (1-3), 264-270 (2007) |
| Description |
This is a synthetic peptide designed for use in combination with anti-PNPO antibody (Catalog #: ARP58515_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
