G6PD Peptide - middle region (AAP58469)

Data Sheet
 
Sku AAP58469
Old sku AAPP34520
Price $99.00
Name G6PD Peptide - middle region (AAP58469)
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Size 100 ug
Gene G6PD
Alias symbols G6PD1
Gene id 2539
Description of target G6PD is a glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.
Swissprot id P11413
Protein accession num NP_000393
Nucleotide accession num NM_000402
Protein size 515 amino acids
Molecular weight 57kDa
Application WB
Partner proteins G6PD,SUMO4,G6PD
Quality control The peptide is characterized by mass spectroscopy
Key reference Langbein,S., (2008) Int. J. Cancer 122 (11), 2422-2428
Description This is a synthetic peptide designed for use in combination with anti-G6PD antibody (Catalog #: ARP58469_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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