| Sku |
AAP58450 |
| Old sku |
AAPP34559 |
| Price |
$99.00 |
| Name |
DCTN2 Peptide - N-terminal region (AAP58450) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
DCTN2 |
| Alias symbols |
DCTN50, DYNAMITIN, RBP50 |
| Gene id |
10540 |
| Description of target |
DCTN2 is a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Swissprot id |
Q13561 |
| Protein accession num |
NP_006391 |
| Nucleotide accession num |
NM_006400 |
| Protein size |
406 amino acids |
| Molecular weight |
45kDa |
| Application |
WB |
| Partner proteins |
DCTN1,BICD1,BICD2,GADD45A,GNAO1,GOLM1,GSK3B,MARCKSL1,RPGR,ZW10,BICD2,CALM1,GADD45A,GNAO1,GOLM1,HGS,MARCKSL1,PAFAH1B1 |
| Subunit |
2 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Camargo,L.M., (2007) Mol. Psychiatry 12 (1), 74-86 |
| Description |
This is a synthetic peptide designed for use in combination with anti-DCTN2 antibody (Catalog #: ARP58450_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
