Sku |
AAP58414 |
Old sku |
AAPP34545 |
Price |
$99.00 |
Name |
ACTR1A Peptide - middle region (AAP58414) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
ACTR1A |
Alias symbols |
ARP1, CTRN1 |
Gene id |
10121 |
Description of target |
ACTR1A is a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
Swissprot id |
P61163 |
Protein accession num |
NP_005727 |
Nucleotide accession num |
NM_005736 |
Protein size |
376 amino acids |
Molecular weight |
41kDa |
Application |
WB |
Partner proteins |
ACTR1A,DCTN1,DCTN4,NUMA1,SPTBN1,SPTBN2,BICD2,DCTN4,NUMA1,SPTBN2 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Sugarbaker,D.J., (2008) Proc. Natl. Acad. Sci. U.S.A. 105 (9), 3521-3526 |
Description |
This is a synthetic peptide designed for use in combination with anti-ACTR1A antibody (Catalog #: ARP58414_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |