| Sku |
AAP58398 |
| Old sku |
AAPP33407 |
| Price |
$99.00 |
| Name |
JMJD2B Peptide - middle region (AAP58398) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
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- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
KDM4B |
| Alias symbols |
FLJ44906, KDM4B, KIAA0876, JMJD2B |
| Gene id |
23030 |
| Description of target |
JMJD2 family proteins are classified into one group with JD2H and TUDOR domains and another group without JD2H or TUDOR domains. Because JMJD2C gene (also known as GASC1 gene) is amplified in esophageal squamous cell carcinoma (ESCC), JMJD2 family genes are cancer-associated genes. Human genes corresponding to KIAA0677, KIAA0876, KIAA0780 and FLJ10251 cDNAs were designated JMJD2A, JMJD2B, JMJD2C, and JMJD2D, respectively. In addition, JMJD2D homologous genes within human genome sequences AP002383.3 and AP001264.4 were designated JMJD2E and JMJD2F, respectively. C2HC2HC2- and C5HC2-type Cys (His) clusters were identified as the region conserved among JMJD2A (1064 aa), JMJD2B (1096 aa), and JMJD2C (1056 aa) proteins. JMJD2A, JMJD2B and JMJD2C consist of JmjN, JmjC, JD2H, and two TUDOR domains. |
| Swissprot id |
O94953 |
| Protein accession num |
NP_055830 |
| Nucleotide accession num |
NM_015015 |
| Protein size |
1096 amino acids |
| Molecular weight |
122kDa |
| Application |
WB |
| Partner proteins |
UBC; H3F3C; HSP90B1; HSP90AA2P; SMU1; KMT2C; WDR5; ASH2L; KMT2D; RBBP5; HSPA4; HNRNPU; ESR1; MED10; |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Katoh,Y. (2007) Int. J. Mol. Med. 20 (2), 269-273 |
| Description |
This is a synthetic peptide designed for use in combination with anti-JMJD2B antibody (Catalog #: ARP58398_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
