USP22 Peptide - middle region (AAP58353)

Data Sheet
 
Sku AAP58353
Old sku AAPP32963
Price $99.00
Name USP22 Peptide - middle region (AAP58353)
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Size 100 ug
Gene USP22
Alias symbols KIAA1063, USP3L
Gene id 23326
Description of target USP22 is a subunit of the SAGA transcriptional cofactor complex. It deubiquitylates histone H2B and is recruited to specific genes by activators like Myc. USP22 is needed for cell cycle progression. It deubiquitylates histone H2A in addition to H2B. Altered mRNA expression is associated with therapy failure and death in patients multiple types of cancer.
Swissprot id Q9UPT9
Protein accession num NP_056091
Nucleotide accession num NM_015276
Protein size 525 amino acids
Molecular weight 60kDa
Application WB
Partner proteins AASDHPPT,ATXN7,ATXN7L2,ATXN7L3,ATXN7L3B,CCDC101,CNOT1,CNOT10,DEDD,ENY2,FAM48A,HEXA,KAT2A,KIF7,KLHL23,MRPL10,POFUT2,PREPL,PSME1,SCFD1,SIRT1,SND1,SUPT3H,SUPT7L,TADA1,TADA2B,TADA3,TAF10,TAF5L,TAF6L,TAF9,TRRAP,USP27X,USP8
Quality control The peptide is characterized by mass spectroscopy
Key reference Zhang,X.Y., (2008) Mol. Cell 29 (1), 102-111
Description This is a synthetic peptide designed for use in combination with anti-USP22 antibody (Catalog #: ARP58353_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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