| Sku |
AAP58280 |
| Old sku |
AAPP32879 |
| Price |
$99.00 |
| Name |
H2AFX Peptide - N-terminal region (AAP58280) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
H2AFX |
| Alias symbols |
H2A.X, H2A/X, H2AX |
| Gene id |
3014 |
| Description of target |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. H2AFX is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Swissprot id |
P16104 |
| Protein accession num |
NP_002096 |
| Nucleotide accession num |
NM_002105 |
| Protein size |
143 amino acids |
| Molecular weight |
16kDa |
| Application |
WB |
| Partner proteins |
ATM,ALG9,ATM,BRCA1,H2AFX,MDC1,MRE11A,NBN,PPP1CA,SUPT5H,TP53BP1,WRN,ATR,BARD1,BLM,BRCA1,MDC1,NBN,PPM1D,RAD50,RAD51,TP53BP1,XPC |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Scherthan,H., (2008) Biochem. Biophys. Res. Commun. 371 (4), 694-697 |
| Description |
This is a synthetic peptide designed for use in combination with anti-H2AFX antibody (Catalog #: ARP58280_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
