Sku |
AAP58266 |
Old sku |
AAPP32865 |
Price |
$99.00 |
Name |
CENPH Peptide (AAP58266) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
CENPH |
Alias symbols |
NNF1, PMF1 |
Gene id |
64946 |
Description of target |
Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. CENPH colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
Swissprot id |
Q9H3R5 |
Protein accession num |
NP_075060 |
Nucleotide accession num |
NM_022909 |
Protein size |
247 amino acids |
Molecular weight |
27kDa |
Application |
WB |
Partner proteins |
CENPH,KIF2C,CENPH,KIF2C,PMVK |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Liao,W.T., Clin. Cancer Res. 13 (2 PT 1), 508-514 (2007) |
Description |
This is a synthetic peptide designed for use in combination with anti-CENPH antibody (Catalog #: ARP58266_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
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Tips |
See our General FAQ page. |
Availability |
In Stock |