| Sku |
AAP58157 |
| Old sku |
AAPP32590 |
| Price |
$99.00 |
| Name |
HMGB2 Peptide - middle region (AAP58157) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
HMGB2 |
| Alias symbols |
HMG2 |
| Gene id |
3148 |
| Description of target |
HMGB2 is a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. HMGB2 was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Swissprot id |
P26583 |
| Protein accession num |
NP_002120 |
| Nucleotide accession num |
NM_002129 |
| Protein size |
209 amino acids |
| Molecular weight |
24kDa |
| Application |
IHC, WB |
| Partner proteins |
APEX1,CSNK1A1,GZMA,PGR,POU2F1,POU2F2,POU3F1,POU5F1,PRKDC,RAG1,SET,TP53,AR,CSNK1A1,GZMA,NR3C1,PGR,POU2F2,POU5F1,RAG1,SET |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
McCauley,M.J., (2007) J. Mol. Biol. 374 (4), 993-1004 |
| Description |
This is a synthetic peptide designed for use in combination with anti-HMGB2 antibody (Catalog #: ARP58157_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
