Sku |
AAP58069 |
Old sku |
AAPP32492 |
Price |
$99.00 |
Name |
SHOX2 Peptide - middle region (AAP58069) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
SHOX2 |
Alias symbols |
OG12, OG12X, OGI2X, SHOT |
Gene id |
6474 |
Description of target |
SHOX2 is a member of the homeo box family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeo box genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeo box genes. SHOX is a pseudoautosomal homeo box gene that is thought to be responsible for idiopathic short stature and implicated to play a role in the short stature phenotype of Turner syndrome patients. This gene is a member of the homeo box family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeo box genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeo box genes. SHOX is a pseudoautosomal homeo box gene that is thought to be responsible for idiopathic short stature and implicated to play a role in the short stature phenotype of Turner syndrome patients. This gene is considered to be a candidate gene for Cornelia de Lange syndrome. Alternative splicing has been observed at this locus and two variants, each encoding a distinct isoform, have been identified. |
Swissprot id |
O60902 |
Protein accession num |
NP_006875 |
Nucleotide accession num |
NM_006884 |
Protein size |
331 amino acids |
Molecular weight |
35kDa |
Application |
WB |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Hillman,R.T., Genome Biol. 5 (2), R8 (2004) |
Description |
This is a synthetic peptide designed for use in combination with anti-SHOX2 antibody (Catalog #: ARP58069_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |