HOXB5 Peptide - N-terminal region (AAP58022)

Data Sheet
 
Sku AAP58022
Old sku AAPP32445
Price $99.00
Name HOXB5 Peptide - N-terminal region (AAP58022)
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Size 100 ug
Gene HOXB5
Alias symbols HHO.C10, HOX2, HOX2A, HU-1, Hox2.1
Gene id 3215
Description of target HOXB5 belongs to ANTP homeobox family. It is a nuclear protein with a homeobox DNA-binding domain. HOXB5 gene is included in a cluster of homeobox B genes located on chromosome 17.The protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue.This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Swissprot id P09067
Protein accession num NP_002138
Nucleotide accession num NM_002147
Protein size 269 amino acids
Molecular weight 29kDa
Application WB
Quality control The peptide is characterized by mass spectroscopy
Key reference Wu,Q., (er) Mol. Cancer 6, 45 (2007)
Description This is a synthetic peptide designed for use in combination with anti-HOXB5 antibody (Catalog #: ARP58022_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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