| Sku |
AAP58011 |
| Old sku |
AAPP32434 |
| Price |
$99.00 |
| Name |
UBE2K Peptide - N-terminal region (AAP58011) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
UBE2K |
| Alias symbols |
DKFZp564C1216, DKFZp686J24237, E2-25K, HIP2, HYPG, LIG, UBC1 |
| Gene id |
3093 |
| Description of target |
UBE2K belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation.The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. |
| Swissprot id |
P61086 |
| Protein accession num |
NP_005330 |
| Nucleotide accession num |
NM_005339 |
| Protein size |
200 amino acids |
| Molecular weight |
22kDa |
| Application |
WB |
| Partner proteins |
HTT,HTT,NEDD8,NFKB1,PIAS4,TP53,TRIM3,DDX58,DSTYK,HTT,RNF2,UBE2I |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Christensen,D.E., (2007) Nat. Struct. Mol. Biol. 14 (10), 941-948 |
| Description |
This is a synthetic peptide designed for use in combination with anti-UBE2K antibody (Catalog #: ARP58011_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
