| Sku |
AAP58007 |
| Old sku |
AAPP32430 |
| Price |
$99.00 |
| Name |
GTF2I Peptide - middle region (AAP58007) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
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|
| Size |
100 ug |
| Gene |
GTF2I |
| Alias symbols |
BAP-135, BAP135, BTKAP1, DIWS, IB291, SPIN, TFII-I, WBS, WBSCR6, GTFII-I |
| Gene id |
2969 |
| Description of target |
GTF2I is a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.This gene encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. The exon(s) encoding 5' UTR has not been fully defined, but this gene is known to contain at least 34 exons, and its alternative splicing generates 4 transcript variants. This gene encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Four transcript variants encoding different isoforms have been found for this gene. |
| Swissprot id |
P78347 |
| Protein accession num |
NP_127492 |
| Nucleotide accession num |
NM_032999 |
| Protein size |
998 amino acids |
| Molecular weight |
112kDa |
| Application |
WB |
| Partner proteins |
ATF6,BTK,GTF2I,HDAC3,JAK2,MAPK3,MYC,NFKB2,PIAS2,PRKG1,PRRX1,SMAD2,SRC,SRF,STAT1,STAT3,USF1,YY1,ZBTB17,ATF6,BTK,HDAC1,HDAC2,HDAC3,HDAC3,KDM1A,MAPK3,MEPCE,MYC,NAA38,NFI1,OTUB2,PHF21A,PRKG1,PRRX1,PTP4A3,Pias2,SRF,STAT1,STAT3,STX7,SUZ12,USF1,USP7 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Ewing,R.M., Mol. Syst. Biol. 3, 89 (2007) |
| Description |
This is a synthetic peptide designed for use in combination with anti-GTF2I antibody (Catalog #: ARP58007_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
