ATF5 Peptide - middle region (AAP57977)

Data Sheet
 
Sku AAP57977
Old sku AAPP32388
Price $99.00
Name ATF5 Peptide - middle region (AAP57977)
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Size 100 ug
Gene ATF5
Alias symbols ATFX, FLJ34666, HMFN0395
Gene id 22809
Description of target ATF5 belongs to the bZIP family. It is transcriptional activator which binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters and blocks the differentiation of neuroprogenitor cells into neurons. Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4. Loss of ATF5 is associated with hepatocellular carcinoma.
Swissprot id B3KND3
Protein accession num NP_036200
Nucleotide accession num NM_012068
Protein size 282 amino acids
Molecular weight 31kDa
Application WB
Partner proteins DISC1,CCND3,CDC34,CEBPG,DISC1,GABBR1,GABBR2,CD34,CDC34,DISC1,GABBR1,TRIB3,UBC
Quality control The peptide is characterized by mass spectroscopy
Key reference Zhou,D., (2008) J. Biol. Chem. 283 (11), 7064-7073
Description This is a synthetic peptide designed for use in combination with anti-ATF5 antibody (Catalog #: ARP57977_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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