Sku |
AAP57956 |
Old sku |
AAPP32367 |
Price |
$99.00 |
Name |
ERCC8 Peptide - middle region (AAP57956) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
ERCC8 |
Alias symbols |
CKN1, CSA |
Gene id |
1161 |
Description of target |
ERCC8 is a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS).This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes. |
Swissprot id |
Q13216 |
Protein accession num |
NP_000073 |
Nucleotide accession num |
NM_000082 |
Protein size |
396 amino acids |
Molecular weight |
44kDa |
Application |
WB |
Partner proteins |
CBR1,DDB1,ERCC6,GTF2H2,UQCRQ,XAB2,COPS5,COPS6,CUL4A,CUL4B,DDB1,XAB2 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Bethke,L., (2008) J. Natl. Cancer Inst. 100 (4), 270-276 |
Description |
This is a synthetic peptide designed for use in combination with anti-ERCC8 antibody (Catalog #: ARP57956_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |