TUB Peptide - N-terminal region (AAP57909)

Data Sheet
 
Sku AAP57909
Old sku AAPP32320
Price $99.00
Name TUB Peptide - N-terminal region (AAP57909)
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Size 100 ug
Gene TUB
Alias symbols rd5
Gene id 7275
Description of target TUB functions in signal transduction from heterotrimeric G protein-coupled receptors. It could be involved in the hypothalamic regulation of body weight.This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene.
Swissprot id P50607
Protein accession num NP_003311
Nucleotide accession num NM_003320
Protein size 561 amino acids
Molecular weight 62kDa
Application WB
Partner proteins ABL1,GNAQ,GRB2,IRS1,JAK2,LCK,PIK3R1,PLCG1,SRC,ABL1,JAK2,PLCG1
Quality control The peptide is characterized by mass spectroscopy
Key reference Snieder,H., (2008) Diabetologia 51 (1), 54-61
Description This is a synthetic peptide designed for use in combination with anti-TUB antibody (Catalog #: ARP57909_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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