| Sku |
AAP57907 |
| Old sku |
AAPP32318 |
| Price |
$99.00 |
| Name |
TFAP2B Peptide - N-terminal region (AAP57907) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
TFAP2B |
| Alias symbols |
AP-2B, AP2-B, MGC21381 |
| Gene id |
7021 |
| Description of target |
TFAP2B belongs to the AP-2 family which is developmentally regulated and have distinct overlapping functions in the regulation of many genes governing growth and differentiation. TFAP2B binds DNA as a dimmer and can form homodimers or heterodimers with other AP-2 family members. It may be a candidate for conferring susceptibility to type 2 didabetes. This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-144 AU141084.1 1-144 145-1684 BC037225.1 1-1540 1685-5370 AL049693.16 11928-15613 5371-5770 BU738725.1 18-417 c |
| Swissprot id |
Q92481 |
| Protein accession num |
NP_003212 |
| Nucleotide accession num |
NM_003221 |
| Protein size |
460 amino acids |
| Molecular weight |
50kDa |
| Application |
WB |
| Partner proteins |
CITED4,HIST1H2AC,MYC,UBE2I,VPS11,YEATS4,CITED1,CITED2,CITED4,GRB2 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Hensch,T., (2008) Neurosci. Lett. 436 (1), 67-71 |
| Description |
This is a synthetic peptide designed for use in combination with anti-TFAP2B antibody (Catalog #: ARP57907_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
