| Sku |
AAP57862 |
| Old sku |
AAPP32215 |
| Price |
$99.00 |
| Name |
ATG4B Peptide - N-terminal region (AAP57862) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
ATG4B |
| Alias symbols |
APG4B, AUTL1, MGC1353 |
| Gene id |
23192 |
| Description of target |
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. ATG4B is a member of the autophagin protein family, it is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
| Swissprot id |
Q9Y4P1 |
| Protein accession num |
NP_037457 |
| Nucleotide accession num |
NM_013325 |
| Protein size |
393 amino acids |
| Molecular weight |
44kDa |
| Application |
WB |
| Partner proteins |
GABARAP,GABARAPL2,MAP1LC3B,C14orf139,FBXW11,GABARAP,GABARAPL2,MAP1LC3B |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Olsen,J.V., (2006) Cell 127 (3), 635-648 |
| Description |
This is a synthetic peptide designed for use in combination with anti-ATG4B antibody (Catalog #: ARP57862_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
