PRKACA Peptide - N-terminal region (AAP57828)

Data Sheet
 
Sku AAP57828
Old sku AAPP43102
Price $99.00
Name PRKACA Peptide - N-terminal region (AAP57828)
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Size 100ug
Gene PRKACA
Alias symbols MGC102831, MGC48865, PKACA
Gene id 5566
Description of target cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Swissprot id A8K8B9
Protein accession num NP_997401
Nucleotide accession num NM_207518
Protein size 343 amino acids
Molecular weight 40kDa
Species reactivity Human
Application WB
Peptide sequence MASNSSDVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRV
Partner proteins NMT1,AANAT,ABCA1,ACCN2,ACLY,ADCY5,ADD1,ADD2,ADRBK1,AKAP14,AKAP8L,APC,ATF1,ATP2B1,AURKA,BAD,BCL2,BRAF,C11orf17,C7orf16,CACNA1C,CACNB2,CACNG2,CAD,CCND1,CDK16,CETN1,CFTR,CIITA,CLDN3,CREM,CSK,CUL5,DNAJC5,DSP,EEF2K,EGFR,EPB49,ESR1,ETV1,FOS,FXYD1,GABRR1,GFAP,GJ
Quality control The peptide is characterized by mass spectroscopy
Key reference N/A
Description This is a synthetic peptide designed for use in combination with anti-PRKACA Antibody(ARP57828_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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