Sku |
AAP57743 |
Old sku |
AAPP35446 |
Price |
$99.00 |
Name |
PSMA3 Peptide - middle region (AAP57743) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
PSMA3 |
Alias symbols |
HC8, MGC12306, MGC32631, PSC3 |
Gene id |
5684 |
Description of target |
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA3 is a member of the peptidase T1A family, that is a 20S core alpha subunit.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified. |
Swissprot id |
P25788-2 |
Protein accession num |
NP_687033 |
Nucleotide accession num |
NM_152132 |
Protein size |
248 amino acids |
Molecular weight |
28kDa |
Application |
WB |
Partner proteins |
ATN1,AURKB,BAT2,CDKN1A,CRYAB,CSNK2A1,EGR1,GFI1B,HHEX,PLK1,PRNP,PSMA1,PSMA2,PSMA4,PSMA6,PSMA7,PSMB5,RERE,SNRPB,SNRPF,STUB1,STX11,XRN2,BAT2,CDKN1A,CRYAB,EGR1,GIYD2,PLK1,PSMA1,PSMA6,PSMD13,PSMD14,SNRPB,SNRPF,STX11,TRIB3,XRN2 |
Subunit |
alpha type-3 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Olsen,J.V., (2006) Cell 127 (3), 635-648 |
Description |
This is a synthetic peptide designed for use in combination with anti-PSMA3 antibody (Catalog #: ARP57743_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |