PSMA3 Peptide - middle region (AAP57743)

Data Sheet
 
Sku AAP57743
Old sku AAPP35446
Price $99.00
Name PSMA3 Peptide - middle region (AAP57743)
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Size 100 ug
Gene PSMA3
Alias symbols HC8, MGC12306, MGC32631, PSC3
Gene id 5684
Description of target The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA3 is a member of the peptidase T1A family, that is a 20S core alpha subunit.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified.
Swissprot id P25788-2
Protein accession num NP_687033
Nucleotide accession num NM_152132
Protein size 248 amino acids
Molecular weight 28kDa
Application WB
Partner proteins ATN1,AURKB,BAT2,CDKN1A,CRYAB,CSNK2A1,EGR1,GFI1B,HHEX,PLK1,PRNP,PSMA1,PSMA2,PSMA4,PSMA6,PSMA7,PSMB5,RERE,SNRPB,SNRPF,STUB1,STX11,XRN2,BAT2,CDKN1A,CRYAB,EGR1,GIYD2,PLK1,PSMA1,PSMA6,PSMD13,PSMD14,SNRPB,SNRPF,STX11,TRIB3,XRN2
Subunit alpha type-3
Quality control The peptide is characterized by mass spectroscopy
Key reference Olsen,J.V., (2006) Cell 127 (3), 635-648
Description This is a synthetic peptide designed for use in combination with anti-PSMA3 antibody (Catalog #: ARP57743_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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