PRELP Peptide - middle region (AAP56412)

Data Sheet
 
Sku AAP56412
Old sku AAPP34209
Price $99.00
Name PRELP Peptide - middle region (AAP56412)
Purchase info To purchase this peptide:
  • Copy peptide sku
  • Click on this link
  • Paste into field "Peptide Sku"
Size 100 ug
Gene PRELP
Alias symbols MGC45323, MST161, MSTP161, SLRR2A
Gene id 5549
Description of target PRELP is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage.The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed.
Swissprot id P51888
Protein accession num NP_002716
Nucleotide accession num NM_002725
Protein size 382 amino acids
Molecular weight 42kDa
Application WB
Partner proteins COL1A1,COL2A1,FBLN2,FN1,HSPG2,NID1,COL1A1,COL2A1,FBLN2,HSPG2,NID2
Quality control The peptide is characterized by mass spectroscopy
Key reference Grover,J., (2007) Matrix Biol. 26 (2), 140-143
Description This is a synthetic peptide designed for use in combination with anti-PRELP antibody (Catalog #: ARP56412_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
Protocol
Tips

See our General FAQ page.

Availability In Stock
 

AVIVA SYSTEMS BIOLOGY manufactures and sells quality antibody products covering genome wide proteins.

AVIVA SYSTEMS BIOLOGY
6370 Nancy Ridge Dr., Suite 104, San Diego, CA 92121 USA | Tel: (858)552-6979 | info@avivasysbio.com