| Sku |
AAP56299 |
| Old sku |
AAPP35502 |
| Price |
$99.00 |
| Name |
SELENOP Peptide - N-terminal region (AAP56299) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
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- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
SELENOP |
| Alias symbols |
SeP, SELP, SEPP, SEPP1 |
| Gene id |
6414 |
| Description of target |
This gene encodes a selenoprotein that is predominantly expressed in the liver and secreted into the plasma. This selenoprotein is unique in that it contains multiple selenocysteine (Sec) residues per polypeptide (10 in human), and accounts for most of the selenium in plasma. It has been implicated as an extracellular antioxidant, and in the transport of selenium to extra-hepatic tissues via apolipoprotein E receptor-2 (apoER2). Mice lacking this gene exhibit neurological dysfunction, suggesting its importance in normal brain function. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. The mRNA for this selenoprotein contains two SECIS elements. Alternatively spliced transcript variants have been found for this gene. |
| Swissprot id |
P49908 |
| Protein accession num |
NP_001087195 |
| Nucleotide accession num |
NM_001093726 |
| Protein size |
411 amino acids |
| Molecular weight |
46kDa |
| Application |
WB |
| Partner proteins |
EP300; MEOX2; THRA; EGFR; |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Peters,U., (2008) Cancer Epidemiol. Biomarkers Prev. 17 (5), 1144-1154 |
| Description |
This is a synthetic peptide designed for use in combination with anti-SEPP1 antibody (Catalog #: ARP56299_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
