HERV-FRD Peptide - N-terminal region (AAP56008)

Data Sheet
 
Sku AAP56008
Old sku AAPP37414
Price $99.00
Name HERV-FRD Peptide - N-terminal region (AAP56008)
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Size 100 ug
Gene ERVFRD-1
Alias symbols FLJ41944, FLJ90611, GLLL6191, MGC87585, UNQ6191, envFRD, ERVFRDE1, HERV-FRD, HERV-W/FRD
Gene id 405754
Description of target Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has retained its original fusogenic properties. HERV-FRD can make pseudotypes with MLV, HIV-1 or SIV-1 virions and confer infectivity.Human endogenous retroviruses (HERVs) make up approximately 8% of the human genome. Although most HERVs are nonfunctional, the HERV-W (ERVWE1; MIM 604659) and HERV-FRD envelope (env) proteins can induce cell-cell fusion when expressed in cells possessing appropriate receptors (Blaise et al., 2003 [PubMed 14557543]).[supplied by OMIM].
Swissprot id P60508
Protein accession num NP_997465
Nucleotide accession num NM_207582
Protein size 538 amino acids
Molecular weight 55kDa
Application WB
Partner proteins APP;
Quality control The peptide is characterized by mass spectroscopy
Key reference Malassine,A., (er) Retrovirology 5, 6 (2008)
Description This is a synthetic peptide designed for use in combination with anti-HERV-FRD antibody (Catalog #: ARP56008_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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