Sku |
AAP56008 |
Old sku |
AAPP37414 |
Price |
$99.00 |
Name |
HERV-FRD Peptide - N-terminal region (AAP56008) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
ERVFRD-1 |
Alias symbols |
FLJ41944, FLJ90611, GLLL6191, MGC87585, UNQ6191, envFRD, ERVFRDE1, HERV-FRD, HERV-W/FRD |
Gene id |
405754 |
Description of target |
Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has retained its original fusogenic properties. HERV-FRD can make pseudotypes with MLV, HIV-1 or SIV-1 virions and confer infectivity.Human endogenous retroviruses (HERVs) make up approximately 8% of the human genome. Although most HERVs are nonfunctional, the HERV-W (ERVWE1; MIM 604659) and HERV-FRD envelope (env) proteins can induce cell-cell fusion when expressed in cells possessing appropriate receptors (Blaise et al., 2003 [PubMed 14557543]).[supplied by OMIM]. |
Swissprot id |
P60508 |
Protein accession num |
NP_997465 |
Nucleotide accession num |
NM_207582 |
Protein size |
538 amino acids |
Molecular weight |
55kDa |
Application |
WB |
Partner proteins |
APP; |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Malassine,A., (er) Retrovirology 5, 6 (2008) |
Description |
This is a synthetic peptide designed for use in combination with anti-HERV-FRD antibody (Catalog #: ARP56008_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |