Sku |
AAP55622 |
Old sku |
AAPP34247 |
Price |
$99.00 |
Name |
SPAG8 Peptide - middle region (AAP55622) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
SPAG8 |
Alias symbols |
BS-84, HSD-1, MGC26201, SMP1, SPAG3, hSMP-1 |
Gene id |
26206 |
Description of target |
The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. SPAG8 is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa.The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein encoded by this gene is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined. |
Swissprot id |
Q99932-2 |
Protein accession num |
NP_758516 |
Nucleotide accession num |
NM_172312 |
Protein size |
501 amino acids |
Molecular weight |
53kDa |
Application |
WB |
Partner proteins |
RAN,UBQLN4 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Cheng,G.Y., (2007) Asian J. Androl. 9 (1), 23-29 |
Description |
This is a synthetic peptide designed for use in combination with anti-SPAG8 antibody (Catalog #: ARP55622_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |