| Sku |
AAP54958 |
| Old sku |
AAPP32119 |
| Price |
$99.00 |
| Name |
UBQLN1 Peptide (AAP54958) |
| Purchase info |
To purchase this peptide:
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|
| Size |
100 ug |
| Gene |
UBQLN1 |
| Alias symbols |
DA41, DSK2, FLJ90054, PLIC-1, XDRP1, UBQN |
| Gene id |
29979 |
| Description of target |
UBQLN1 is an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene.This gene encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene. |
| Swissprot id |
Q5T6J9 |
| Protein accession num |
NP_038466 |
| Nucleotide accession num |
NM_013438 |
| Protein size |
589 amino acids |
| Molecular weight |
62kDa |
| Application |
IHC, WB |
| Partner proteins |
HCVgp1,ADRM1,ASCL1,ATXN3,CD47,CD99,CHRNA3,CHRNA4,CHRNB4,CSTF2,CSTF2T,DNAJB2,EFEMP2,EPS15,FAM127A,FAM127B,FZD7,GABRA3,GABRD,GKAP1,HES1,HGS,HK2,HSPA13,KLHDC5,MTOR,NBL1,P4HB,PLA2G16,PRPF40A,PSEN1,PSEN2,PSMD4,RASSF5,RIC8A,SERPINI2,SMAD9,SMCR7,TFF1,TMCO6,TRIM32,UBQLN1,UBQLN4,ZG16,CD99,CSTF2,CSTF2T,EFEMP2,FAM127B,FZD7,GABRD,HERC3,HERPUD1,HGS,HK2,HSPA13,IGLC1,KLHDC5,MTOR,NBL1,P4HB,PLA2G16,PSEN1,PSEN2,RIC8A,SERPINI2,SMCR7,TFF1,TMCO6,TRIM32,UBE3A,UBQLN1 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Zhang,D., (2008) J. Mol. Biol. 377 (1), 162-180 |
| Description |
This is a synthetic peptide designed for use in combination with anti-UBQLN1 antibody (Catalog #: ARP54958_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
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