| Sku |
AAP54884 |
| Old sku |
AAPP31686 |
| Price |
$99.00 |
| Name |
GTPBP4 Peptide - C-terminal region (AAP54884) |
| Purchase info |
To purchase this peptide:
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|
| Size |
100 ug |
| Gene |
GTPBP4 |
| Alias symbols |
CRFG, FLJ10686, FLJ10690, FLJ39774, NGB, NOG1 |
| Gene id |
23560 |
| Description of target |
GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target.GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target. |
| Swissprot id |
Q9BZE4 |
| Protein accession num |
NP_036473 |
| Nucleotide accession num |
NM_012341 |
| Protein size |
634 amino acids |
| Molecular weight |
74kDa |
| Application |
WB |
| Partner proteins |
YWHAG,EIF6,LYAR,PINX1 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Lee,H., (2007) Mol. Cell. Biol. 27 (6), 2103-2119 |
| Description |
This is a synthetic peptide designed for use in combination with anti-GTPBP4 antibody (Catalog #: ARP54884_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
