CDC42EP4 Peptide - N-terminal region (AAP54839)

Data Sheet
 
Sku AAP54839
Old sku AAPP31643
Price $99.00
Name CDC42EP4 Peptide - N-terminal region (AAP54839)
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Size 100 ug
Gene CDC42EP4
Alias symbols BORG4, CEP4, KAIA1777, MGC17125, MGC3740
Gene id 23580
Description of target CDC42EP4 is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. The protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, the protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control.The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control.
Swissprot id Q9H3Q1
Protein accession num NP_036253
Nucleotide accession num NM_012121
Protein size 356 amino acids
Molecular weight 38kDa
Application WB
Partner proteins RHOQ,TGFBR1,WDR6,POLR3H,WDR6
Quality control The peptide is characterized by mass spectroscopy
Key reference Olsen,J.V., (2006) Cell 127 (3), 635-648
Description This is a synthetic peptide designed for use in combination with anti-CDC42EP4 antibody (Catalog #: ARP54839_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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