Sku |
AAP54780 |
Old sku |
AAPP31575 |
Price |
$99.00 |
Name |
LOXL1 Peptide (AAP54780) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
LOXL1 |
Alias symbols |
LOL, LOXL |
Gene id |
4016 |
Description of target |
LOXL1 is a member of the lysyl oxidase family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
Swissprot id |
Q08397 |
Protein accession num |
NP_005567 |
Nucleotide accession num |
NM_005576 |
Protein size |
574 amino acids |
Molecular weight |
53kDa |
Application |
WB |
Partner proteins |
ELN,FBLN5,FBLN5 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Ozaki,M., (er) Invest. Ophthalmol. Vis. Sci. (2008) In press |
Description |
This is a synthetic peptide designed for use in combination with anti-LOXL1 antibody (Catalog #: ARP54780_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
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Tips |
See our General FAQ page. |
Availability |
In Stock |