Sku |
AAP54608 |
Old sku |
AAPP31392 |
Price |
$99.00 |
Name |
FES Peptide (AAP54608) |
Purchase info |
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|
Size |
100 ug |
Gene |
FES |
Alias symbols |
FPS |
Gene id |
2242 |
Description of target |
FES is the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. FES has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis. This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis. A truncated transcript has been identified that is generated utilizing a start site in one of the far downstream exons but a protein product associated with this transcript has not been identified. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
Swissprot id |
P07332 |
Protein accession num |
NP_001996 |
Nucleotide accession num |
NM_002005 |
Protein size |
822 amino acids |
Molecular weight |
93kDa |
Application |
WB |
Partner proteins |
BCAR1,BCR,CSF2RB,DOK1,DPYSL5,FES,HSH2D,IL4R,IRS1,IRS2,JAK1,JAK2,JAK3,PIK3R1,PLXNA1,RASA1,RASA3,STAT3,BCAR1,BCR,FKBP4,FKBP5,HSH2D,HSP90AA1,HSPA4,PIK3R1,PPID,PSMD13,PTGES3,STAT3 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Naba,A., (2008) EMBO J. 27 (1), 38-50 |
Description |
This is a synthetic peptide designed for use in combination with anti-FES antibody (Catalog #: ARP54608_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
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Tips |
See our General FAQ page. |
Availability |
In Stock |