FES Peptide (AAP54608)

Data Sheet
 
Sku AAP54608
Old sku AAPP31392
Price $99.00
Name FES Peptide (AAP54608)
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Size 100 ug
Gene FES
Alias symbols FPS
Gene id 2242
Description of target FES is the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. FES has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis. This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis. A truncated transcript has been identified that is generated utilizing a start site in one of the far downstream exons but a protein product associated with this transcript has not been identified. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Swissprot id P07332
Protein accession num NP_001996
Nucleotide accession num NM_002005
Protein size 822 amino acids
Molecular weight 93kDa
Application WB
Partner proteins BCAR1,BCR,CSF2RB,DOK1,DPYSL5,FES,HSH2D,IL4R,IRS1,IRS2,JAK1,JAK2,JAK3,PIK3R1,PLXNA1,RASA1,RASA3,STAT3,BCAR1,BCR,FKBP4,FKBP5,HSH2D,HSP90AA1,HSPA4,PIK3R1,PPID,PSMD13,PTGES3,STAT3
Quality control The peptide is characterized by mass spectroscopy
Key reference Naba,A., (2008) EMBO J. 27 (1), 38-50
Description This is a synthetic peptide designed for use in combination with anti-FES antibody (Catalog #: ARP54608_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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