| Sku |
AAP53757 |
| Old sku |
AAPP30595 |
| Price |
$99.00 |
| Name |
MLF1 Peptide (AAP53757) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
MLF1 |
| Gene id |
4291 |
| Description of target |
MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. It interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. MLF1 suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest.It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus. |
| Swissprot id |
P58340 |
| Protein accession num |
NP_071888 |
| Nucleotide accession num |
NM_022443 |
| Protein size |
268 amino acids |
| Molecular weight |
29kDa |
| Application |
WB |
| Partner proteins |
COPS3,COPS3,GRIK5,MAGEA11,MLF1IP,NRBP1,YWHAZ,GRIK5,MAGEA11 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Li,Z.F., J. Neurol. Sci. 264 (1-2), 77-86 (2008) |
| Description |
This is a synthetic peptide designed for use in combination with anti-MLF1 antibody (Catalog #: ARP53757_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
