| Sku |
AAP53652 |
| Old sku |
AAPP30492 |
| Price |
$99.00 |
| Name |
PRKAA1 Peptide - middle region (AAP53652) |
| Purchase info |
To purchase this peptide:
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|
| Size |
100 ug |
| Gene |
PRKAA1 |
| Alias symbols |
AMPK, AMPKa1, MGC33776, MGC57364 |
| Gene id |
5562 |
| Description of target |
PRKAA1 belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. |
| Swissprot id |
Q13131 |
| Protein accession num |
NP_006242 |
| Nucleotide accession num |
NM_006251 |
| Protein size |
559 amino acids |
| Molecular weight |
63kDa |
| Application |
WB |
| Partner proteins |
ACACA,CAB39,CFTR,EEF2K,GRIK2,MTOR,PFKFB2,PRKAB1,PRKAB2,PRKAG1,PRKAG3,RAF1,TOMM34,CFTR,FNIP1,MTOR,PRKAG1,TSC2 |
| Subunit |
alpha-1 |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Hasumi,H., Gene 415 (1-2), 60-67 (2008) |
| Description |
This is a synthetic peptide designed for use in combination with anti-PRKAA1 antibody (Catalog #: ARP53652_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
