MTPN Peptide - middle region (AAP52859)

Data Sheet
 
Sku AAP52859
Old sku AAPP33916
Price $99.00
Name MTPN Peptide - middle region (AAP52859)
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Size 100 ug
Gene MTPN
Alias symbols FLJ31098, GCDP, V-1
Gene id 136319
Description of target MTPN has a potential role in cerebellar morphogenesis. MTPN may function in differentiation of cerebellar neurons, particularly of granule cells. MTPN seems to be associated with cardiac hypertrophy.The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. This protein also has a potential function in cerebellar morphogenesis, and it may be involved in the differentiation of cerebellar neurons, particularly of granule cells. A cryptic ORF at the 3' end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6.4 kDa tumor antigen that is associated with myeloproliferative disease.
Swissprot id P58546
Protein accession num NP_665807
Nucleotide accession num NM_145808
Protein size 118 amino acids
Molecular weight 13kDa
Application WB
Partner proteins CAPZB,NFKB1,RELA,DSTYK,NFKB1,REL,RELA
Quality control The peptide is characterized by mass spectroscopy
Key reference Xiong,Z., (2006) J. Immunol. 177 (7), 4907-4916
Description This is a synthetic peptide designed for use in combination with anti-MTPN antibody (Catalog #: ARP52859_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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