NUP50 Peptide (AAP52288)

Data Sheet
 
Sku AAP52288
Old sku AAPS30802
Price $99.00
Name NUP50 Peptide (AAP52288)
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Size 100 ug
Gene NUP50
Alias symbols MGC39961, NPAP60, NPAP60L
Gene id 10762
Description of target The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. NUP50 is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import.The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. Pseudogenes of this gene are found on chromosomes 5, 6, and 14. Two transcript variants encoding different isoforms have been found for this gene.
Swissprot id Q9UKX7
Protein accession num NP_009103
Nucleotide accession num NM_007172
Protein size 468 amino acids
Molecular weight 50kDa
Application IF, WB
Partner proteins CDKN1B,KPNA2,KPNB1,RAN,XPO1,BTBD12,CDKN1B,IPO13,KPNA2,KPNB1,NUP153
Quality control The peptide is characterized by mass spectroscopy
Key reference Olsen,J.V., (2006) Cell 127 (3), 635-648
Description This is a synthetic peptide designed for use in combination with anti-NUP50 antibody (Catalog #: ARP52288_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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