| Sku |
AAP51893 |
| Old sku |
AAPP40072 |
| Price |
$99.00 |
| Name |
COPA Peptide (AAP51893) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
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|
| Size |
100 ug |
| Gene |
COPA |
| Alias symbols |
FLJ26320, HEP-COP |
| Gene id |
1314 |
| Description of target |
In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone.In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms. |
| Swissprot id |
P53621 |
| Protein accession num |
NP_004362 |
| Nucleotide accession num |
NM_004371 |
| Protein size |
1224 amino acids |
| Molecular weight |
135kDa |
| Application |
WB |
| Partner proteins |
COPE,SACM1L,ARCN1,ARFGAP1,COPB2,COPE,MTNR1B,PDGFRB,SACM1L,SLC25A11,STX8,TMED2,ARFGAP1,BET1L,COPB1,COPB2,COPE,PDGFRB,SLC25A11,USP49 |
| Subunit |
alpha |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Olsen,J.V., (2006) Cell 127 (3), 635-648 |
| Description |
This is a synthetic peptide designed for use in combination with anti-COPA antibody (Catalog #: ARP51893_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
