Sku |
AAP51761 |
Old sku |
AAPP40136 |
Price |
$99.00 |
Name |
CYP1B1 Peptide (AAP51761) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
CYP1B1 |
Alias symbols |
CP1B, GLC3A, P4501B1, CYPIB1 |
Gene id |
1545 |
Description of target |
CYP1B1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP1B1 localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
Swissprot id |
Q16678 |
Protein accession num |
NP_000095 |
Nucleotide accession num |
NM_000104 |
Protein size |
543 amino acids |
Molecular weight |
61kDa |
Application |
WB |
Partner proteins |
SAE1 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Ikeda,S., (2008) Am. J. Gastroenterol. 103 (6), 1476-1487 |
Description |
This is a synthetic peptide designed for use in combination with anti-CYP1B1 antibody (Catalog #: ARP51761_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |