| Sku |
AAP51359 |
| Old sku |
AAPS23611 |
| Price |
$99.00 |
| Name |
OAS1 Peptide - middle region (AAP51359) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
OAS1 |
| Alias symbols |
IFI-4, OIAS, OIASI |
| Gene id |
4938 |
| Description of target |
This protein is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication.This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described. |
| Swissprot id |
P00973-3 |
| Protein accession num |
NP_001027581 |
| Nucleotide accession num |
NM_001032409 |
| Protein size |
414 amino acids |
| Molecular weight |
47kDa |
| Application |
IHC, WB |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Phosri,C., Mycol. Res. 111 (PT 3), 275-286 (2007) |
| Description |
This is a synthetic peptide designed for use in combination with anti-OAS1 antibody (Catalog #: ARP51359_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
