Sku |
AAP51267 |
Old sku |
AAPP28415 |
Price |
$99.00 |
Name |
PARK7 Peptide - C-terminal region (AAP51267) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
PARK7 |
Alias symbols |
DJ-1, DJ1, FLJ27376 |
Gene id |
11315 |
Description of target |
PARK7 belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7.The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. |
Swissprot id |
Q99497 |
Protein accession num |
NP_009193 |
Nucleotide accession num |
NM_007262 |
Protein size |
189 amino acids |
Molecular weight |
20kDa |
Application |
IHC, WB |
Partner proteins |
DAXX,EFCAB6,PARK7,PIAS2,PPP2R1A,PPP2R1B,SUMO1,C19orf62,EFCAB6,PIAS2,USP19 |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Mellick,G.D., (er) Parkinsonism Relat. Disord. (2008) In press |
Description |
This is a synthetic peptide designed for use in combination with anti-PARK7 antibody (Catalog #: ARP51267_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |