PARK7 Peptide - C-terminal region (AAP51267)

Data Sheet
 
Sku AAP51267
Old sku AAPP28415
Price $99.00
Name PARK7 Peptide - C-terminal region (AAP51267)
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Size 100 ug
Gene PARK7
Alias symbols DJ-1, DJ1, FLJ27376
Gene id 11315
Description of target PARK7 belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7.The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.
Swissprot id Q99497
Protein accession num NP_009193
Nucleotide accession num NM_007262
Protein size 189 amino acids
Molecular weight 20kDa
Application IHC, WB
Partner proteins DAXX,EFCAB6,PARK7,PIAS2,PPP2R1A,PPP2R1B,SUMO1,C19orf62,EFCAB6,PIAS2,USP19
Quality control The peptide is characterized by mass spectroscopy
Key reference Mellick,G.D., (er) Parkinsonism Relat. Disord. (2008) In press
Description This is a synthetic peptide designed for use in combination with anti-PARK7 antibody (Catalog #: ARP51267_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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