NAGS Peptide (AAP51183)

Data Sheet
 
Sku AAP51183
Old sku AAPP28052
Price $99.00
Name NAGS Peptide (AAP51183)
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Size 100 ug
Gene NAGS
Alias symbols AGAS, ARGA, MGC133025
Gene id 162417
Description of target NAGS is a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.
Swissprot id Q8N159
Protein accession num NP_694551
Nucleotide accession num NM_153006
Protein size 534 amino acids
Molecular weight 58kDa
Application WB
Partner proteins TMEM39B
Quality control The peptide is characterized by mass spectroscopy
Key reference Schmidt,E., (2005) Biochim. Biophys. Acta 1740 (1), 54-59
Description This is a synthetic peptide designed for use in combination with anti-NAGS antibody (Catalog #: ARP51183_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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