Sku |
AAP51183 |
Old sku |
AAPP28052 |
Price |
$99.00 |
Name |
NAGS Peptide (AAP51183) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
NAGS |
Alias symbols |
AGAS, ARGA, MGC133025 |
Gene id |
162417 |
Description of target |
NAGS is a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia. |
Swissprot id |
Q8N159 |
Protein accession num |
NP_694551 |
Nucleotide accession num |
NM_153006 |
Protein size |
534 amino acids |
Molecular weight |
58kDa |
Application |
WB |
Partner proteins |
TMEM39B |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Schmidt,E., (2005) Biochim. Biophys. Acta 1740 (1), 54-59 |
Description |
This is a synthetic peptide designed for use in combination with anti-NAGS antibody (Catalog #: ARP51183_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |