GTF2A1L Peptide (AAP50819)

Data Sheet
 
Sku AAP50819
Old sku AAPS29911
Price $99.00
Name GTF2A1L Peptide (AAP50819)
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Size 100 ug
Gene GTF2A1L
Alias symbols ALF, MGC26254
Gene id 11036
Description of target The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology.The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology. Alternative splicing for this locus has been observed and two variants, encoding distinct isoforms, have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
Swissprot id Q9UNN4
Protein accession num NP_006863
Nucleotide accession num NM_006872
Protein size 478 amino acids
Molecular weight 52kDa
Application WB
Partner proteins ASCL3,CSNK2A1,CSNK2A2,GTF2A2,ID3,SUB1,TBP
Quality control The peptide is characterized by mass spectroscopy
Key reference Kim,M., (2006) J. Biol. Chem. 281 (45), 34288-34298
Description This is a synthetic peptide designed for use in combination with anti-GTF2A1L antibody (Catalog #: ARP50819_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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