XYLT2 Peptide (AAP49703)

Data Sheet
 
Sku AAP49703
Old sku AAPP29284
Price $99.00
Name XYLT2 Peptide (AAP49703)
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Size 100 ug
Gene XYLT2
Alias symbols XT-II, XT2, xylT-II, PXYLT2
Gene id 64132
Description of target XYLT2 is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis.The protein encoded by this gene is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Swissprot id Q9H1B5
Protein accession num NP_071450
Nucleotide accession num NM_022167
Protein size 865 amino acids
Molecular weight 97kDa
Application WB
Quality control The peptide is characterized by mass spectroscopy
Key reference Casanova,J.C., (2008) Biochem. Biophys. Res. Commun. 365 (4), 678-684
Description This is a synthetic peptide designed for use in combination with anti-XYLT2 antibody (Catalog #: ARP49703_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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