Sku |
AAP49703 |
Old sku |
AAPP29284 |
Price |
$99.00 |
Name |
XYLT2 Peptide (AAP49703) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
XYLT2 |
Alias symbols |
XT-II, XT2, xylT-II, PXYLT2 |
Gene id |
64132 |
Description of target |
XYLT2 is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis.The protein encoded by this gene is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
Swissprot id |
Q9H1B5 |
Protein accession num |
NP_071450 |
Nucleotide accession num |
NM_022167 |
Protein size |
865 amino acids |
Molecular weight |
97kDa |
Application |
WB |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Casanova,J.C., (2008) Biochem. Biophys. Res. Commun. 365 (4), 678-684 |
Description |
This is a synthetic peptide designed for use in combination with anti-XYLT2 antibody (Catalog #: ARP49703_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |