Sku |
AAP49389 |
Old sku |
AAPY02658 |
Price |
$99.00 |
Name |
PCDHGC4 Peptide (AAP49389) |
Purchase info |
To purchase this peptide:
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|
Size |
100 ug |
Gene |
PCDHGC4 |
Alias symbols |
MGC119489, PCDH-GAMMA-C4 |
Gene id |
56098 |
Description of target |
PCDHGC4 is a single-pass type I membrane protein. It contains 6 cadherin domains.PCDHGC4 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. |
Swissprot id |
Q9Y5F7 |
Protein accession num |
NP_061751 |
Nucleotide accession num |
NM_018928 |
Protein size |
938 amino acids |
Molecular weight |
98kDa |
Application |
IHC, WB |
Quality control |
The peptide is characterized by mass spectroscopy |
Key reference |
Wu,Q., (2001) Genome Res. 11 (3), 389-404 |
Description |
This is a synthetic peptide designed for use in combination with anti-PCDHGC4 antibody (Catalog #: ARP49389_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
Product format |
Lyophilized powder |
Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
Protocol |
|
Tips |
See our General FAQ page. |
Availability |
In Stock |