| Sku |
AAP48940 |
| Old sku |
AAPP28987 |
| Price |
$99.00 |
| Name |
SETD7 Peptide (AAP48940) |
| Purchase info |
To purchase this peptide:
- Copy peptide sku
- Click on this link
- Paste into field "Peptide Sku"
|
| Size |
100 ug |
| Gene |
SETD7 |
| Alias symbols |
FLJ21193, KIAA1717, KMT7, SET7, SET7/9, SET9 |
| Gene id |
80854 |
| Description of target |
SETD7 is a histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. It plays a central role in the transcriptional activation of genes such as collagenase or insulin. It is recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. It has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. |
| Swissprot id |
Q8WTS6 |
| Protein accession num |
NP_085151 |
| Nucleotide accession num |
NM_030648 |
| Protein size |
366 amino acids |
| Molecular weight |
41kDa |
| Application |
WB |
| Partner proteins |
HCFC1,HIST2H3C,HIST3H3,TAF10,TAF7,TP53,L3MBTL |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Subramanian,K., (2008) Mol. Cell 30 (3), 336-347 |
| Description |
This is a synthetic peptide designed for use in combination with anti-SETD7 antibody (Catalog #: ARP48940_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
