HADHB Peptide (AAP48133)

Data Sheet
 
Sku AAP48133
Old sku AAPP28649
Price $99.00
Name HADHB Peptide (AAP48133)
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Size 100 ug
Gene HADHB
Alias symbols MGC87480, MSTP029, TP-BETA, ECHB, MTPB
Gene id 3032
Description of target HADHB is the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. Mutations in HADHB gene result in trifunctional protein deficiency. The protein can also bind RNA and decreases the stability of some mRNAs.This gene encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. Mutations in this gene result in trifunctional protein deficiency. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. Alternatively spliced transcript variants have been found; however, their full-length nature is not known. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Swissprot id P55084
Protein accession num NP_000174
Nucleotide accession num NM_000183
Protein size 474 amino acids
Molecular weight 47kDa
Application WB, IHC
Partner proteins APP,TNNI3K,TNNI3K
Subunit beta, mitochondrial
Quality control The peptide is characterized by mass spectroscopy
Key reference Wang,R., (2006) Zhonghua Fu Chan Ke Za Zhi 41 (10), 672-675
Description This is a synthetic peptide designed for use in combination with anti-HADHB antibody (Catalog #: ARP48133_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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