MAPT Peptide (AAP48103)

Data Sheet
 
Sku AAP48103
Old sku AAPS21802
Price $99.00
Name MAPT Peptide (AAP48103)
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Size 100 ug
Gene MAPT
Alias symbols DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, TAU
Gene id 4137
Description of target MAPT is differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. The mutations in the gene have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Swissprot id P10636-8
Protein accession num NP_005901
Nucleotide accession num NM_005910
Protein size 441 amino acids
Molecular weight 46kDa
Application IHC, WB
Partner proteins YWHAZ,GSK3B,AATF,ABL1,ACTB,APOE,CALM1,CAMK2A,CASP1,CASP3,CASP6,CASP7,CASP8,CDK1,CDK5,CDK5,CDK5,FLJ10357,FYN,GSK3A,GSK3B,HSPA8,MAPK12,MAPT,MARK1,MARK4,OGT,PHKG1,PIN1,PKN1,PPP2CA,PPP2CB,PPP2R5A,PPP5C,PRKCD,PSEN1,RPS6KA3,RPS6KB1,S100B,SNCA,SPTB,STAU1,STUB1,STXBP1,TUBA4A,TUBB,UBB,USP9Y,YWHAB,YWHAZ,AATF,APOE,BAG1,CALM1,FYN,HSPA8,MARK4,PARK2,PIN1,PSEN1,S100B,SNCA,STUB1,STXBP1,UBC,YWHAB,YWHAB,YWHAZ
Quality control The peptide is characterized by mass spectroscopy
Key reference Reynolds,M.R., (2006) Biochemistry 45 (13), 4314-4326
Description This is a synthetic peptide designed for use in combination with anti-MAPT antibody (Catalog #: ARP48103_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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